AJIPHASE Synthesis
How AJIPHASE Works The AJIPHASE® technology employs the use of an anchor, instead of a resin, which provides a homogeneous mixture. After the reaction occurs, the anchor, which is very not soluble in polar solvents, precipitates and is filtered out with the excess reagents and byproducts, providing the recovered intermediate, all in one reactor.
Quality and purity profiles show no difference between AJIPHASE and traditional solid phase synthesis.
Oligonucleotides Using AJIPHASE technology, our skilled scientists are able to cGMP manufacture commercial quantities of many types of oligonucleotides with impurity profiles that match traditional solid phase synthesis.
With no additional special equipment, we are able to produce to 200 kg scale under cGMP with less solvents and reagents required. Providing our customers with cost savings.
PMOs Proven to 8,000 L scale, using our AJIPHASE technology, we are able to produce highly pure PMOs, with impurity profiles that match traditional solid phase synthesis.
Peptides With AJIPHASE, we are able to produce highly pure peptides with no isolation required in kg quantities under cGMP.